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One Thought on “Session 3: Innovative Solutions To Common Perfusion Challenges Using Oxygen Manipulation”

  1. Charlie Krumholz
    April 13, 2017 at 11:00 am

    Gary,
    Thank you very much for this very clear explanation of these mechanisms. I have been an advocate of hyperoxia for some time since a meeting in New York city during which Carl Bocchio (sp?) talked about diving and nitrogen. I still do not pretend to understand everything I need to know about reactive oxygen species and inflammatory mediators. We have cut our blood use to 10% for intra-operative and post-operative transfusion in 2015 and 2016 for 478 patients on CPB…adult. I use hyperoxia, small prime (800ccs),VAVD, less fluid by Anesthesia and hemoconcentration on 70% of my patients. Stroke was 1.5% in 2015, 0.8% mortality for CABG, 1.4% mortality for all 478 patients. It has gone up since then, but AKI was 2.8% in 2015, down from 7% in 2012. So far this year transfusion has risen dramatically. Still, our nadir hematocrit is over 26% so we will see what AKI does this year. Cheers! This is fantastic. Charlie

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Perfusion Theory is an educational platform for the Oxygen Pressure Field Theory (OPFT). August Krogh’s theoretical concept of the oxygen pressure field is explained and then applied to clinical applications in perfusion practice.