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Special equipment has detected gaseous microemboli (GME) in the cerebral circulation of all types of patients on CPB who were tested. By extension, the assumption can be made that most, if not all CPB patients are exposed to GME. The GME are most numerous during interventions by perfusionists and were associated with the worst neuropsychological outcomes.

Perfusion Theory is an educational platform for the Oxygen Pressure Field Theory (OPFT). August Krogh’s theoretical concept of the oxygen pressure field is explained and then applied to clinical applications in perfusion practice.