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As the ventilator FiO2 was reduced, the arterial paO2 dropped to approximately 100 mmHg. This resulted in a reduction of axial vectors and the formation of an anoxic lethal corner. Metabolic acidosis started in the lethal corner and the patient developed an increased base deficit. Upon subsequently increasing the ventilator FiO2, the arterial paO2 was restored to approximately 150 mmHg and the lethal corner was again obliterated by axial vectors of oxygen.

Perfusion Theory is an educational platform for the Oxygen Pressure Field Theory (OPFT). August Krogh’s theoretical concept of the oxygen pressure field is explained and then applied to clinical applications in perfusion practice.