Oxygen Pressure Field Theory Origins

August Krogh

OPFT was first described by August Krogh in 1918. This concept combined with his many other notable achievements in physiology resulted in his being awarded an unshared Noble Prize in Physiology/Medicine in 1920. But, it wasn’t until the 1960’s that microvascular probes were developed that could actually measure the oxygen pressure field, confirming the values predicted by Krogh half a century earlier.

Perfusion Theory is an educational platform for the Oxygen Pressure Field Theory (OPFT). August Krogh’s theoretical concept of the oxygen pressure field is explained and then applied to clinical applications in perfusion practice.